The March 7th edition of WWE SmackDown airs live on the USA Network from the Bankers Life Fieldhouse in Indianapolis, IN at 8 PM ET.
- SmackDown commissioner Shane McMahon and general manager Daniel Bryan are out to the ring first to open up the show. McMahon and Bryan discuss who should get the shot at Bray Wyatt's WWE Championship at WrestleMania. They say they can't decide on who should get the Title shot, so there's one way to settle this: AJ Styles vs. Randy Orton in a singles match tonight to decide who will face Bray Wyatt at WrestleMania.
- Back from commercial, AJ Styles confronts Bryan and McMahon and says they've been ducking him and they're making a huge mistake. AJ says there's a conspiracy against him, but he's going to make the best of a bad situation and take out Orton.
- John Cena & Nikki Bella def. James Ellsworth & Carmella: Before the match, Ellsworth cuts a promo about how he had better luck beating AJ Styles than Cena did. Ellsworth says he's the mack daddy of SmackDown, and he's the man who puts the "mack" in "SmackDown." Ellsworth introduces his "friend who's a girl" Carmella, and things get started. As soon as the opening bell rings, The Miz's entrance music hits and he makes his way to ringside with Maryse. Carmella takes advantage of the distraction and boots Nikki in the face. Carmella continues working on Nikki until Nikki gets the tag to Cena, and thus Ellsworth must enter the match. Ellsworth tries to run away from Cena but Carmella shoves him back towards Cena. Cena hits a back suplex on Ellsworth. Carmella gets in Cena's face and Nikki lays her out. Cena and Nikki both do the Five Knuckle Shuffle on each opponent, then hit the Attitude Adjustment, and they put Carmella and Ellsworth in STF's for the win. After the match, The Miz and Maryse beat down Cena and Nikki. The Miz cuts a promo saying Cena's relationship with Nikki is a lie and it disgusts him. Miz says when it's true love, you don't make the girl sign a contract to be his girlfriend.
- Dean Ambrose is out to the ring to call out Baron Corbin to fight him right now. Corbin shows up on the big screen and declines, so Ambrose says he's going to go find him.
- Mojo Rawley does an interview about his plans for WrestleMania, and Dolph Ziggler interrupts and gets in his face. Ziggler tells him not to reach too hard for the brass ring, and walks off.
- Dean Ambrose is looking for Baron Corbin in the loading area of the arena, but Corbin finds him first with a steel pipe. Corbin beats down Ambrose with the pipe then positions him under the front of a forklift. Corbin sits in the forklift and lowers the fork down onto Ambrose on the ground. Some referees run in and try to physically lift the fork up off of Ambrose, which of course they fail at. Someone finally gets in the forklift and raises the fork off Ambrose.
- Alexa Bliss and Mickie James come out to the ring and cut a promo on Becky Lynch until eventually Becky comes out. Becky says she's going to take the Women's Title back at WrestleMania, but then Natalya interrupts and says she is the rightful #1 contender to the Women's Championship. Mickie James grabs the mic and seems to be under the impression that she is in line for the Women's Championship match at WrestleMania. Becky says she beat Mickie twice so she should have the Title shot, and Natalya says Mickie has a stupid ugly face. Daniel Bryan comes out and says he thinks Alexa should have to defend her Championship against every woman on the SmackDown roster. Bryan says he took some tips about being GM from Teddy Long, and he makes a tag team match.
- Alexa Bliss & Mickie James def. Becky Lynch & Natalya: Natalya starts off against Alexa and she botches a running dropkick spot early on. Natalya forcefully tags in Becky and Alexa Bliss drops Becky with a clothesline. Becky comes back and hits some elbow drops and leg drops for a two count. Alexa rolls outside and Becky follows up with a flying forearm off the apron. Becky knocks Mickie off the apron, so Mickie trips her from ringside and Alexa starts beating down Becky in the ring. Alexa and Mickie take turns working on Becky in the ring. Becky finally starts fighting back with some kicks and a running forearm to Mickie, but Natalya runs in and hits a German suplex on Becky out of nowhere. Natalya walks off, and Alexa pins Becky for the win. After the match, Mickie hits a spinning kick to Alexa's face and leaves her laying in the ring.
- We see a video of Austin Aries saying he's going to explain his attack on Neville on RAW and his plans for the future on 205 Live.
- AJ Styles comes out to the ring and says he only gets disrespect from Shane McMahon and Daniel Bryan. Styles points out that he gets disrespected, meanwhile Randy Orton "burns down a man's house and gets rewarded for it." The main event is up next.
- Randy Orton def. AJ Styles: JBL and Mauro call this one the biggest main event in SmackDown history. Orton goes for an RKO right off the bat, but AJ escapes and rolls outside. AJ gets Orton in a headlock which Orton struggles to get out of, despite dropping AJ with a back suplex. Orton finally breaks free and unleashes some offense on Styles including a t-bone suplex that sends AJ rolling out to ringside. Back in the ring, AJ drops Orton with a shot to the left leg. Styles continues working on the leg of Orton with kicks and holds. Orton comes back and hits AJ with a spinning powerslam and then a full nelson slam. Orton takes Styles to the top turnbuckle for a superplex, but AJ escapes and drops Orton face-first on the top turnbuckle. AJ grabs Orton and hits a fireman's carry into a backbreaker for a two count. AJ goes for the Styles Clash, but Orton gets out and drops AJ out to the ring apron. Orton attempts his patented draping DDT over the middle rope, but AJ escapes and locks Orton in the Calf Crusher on his left leg. Orton grabs the ropes to break the hold. AJ goes for a Phenomenal Forearm, but Orton knocks him off the rope and hits his draping DDT. Orton goes for the RKO, but AJ gets out and hits the Pele kick. AJ goes for a Phenomenal Forearm, but fakes out Orton and Orton misses an RKO attempt. AJ goes back to the top rope and goes for a 450 splash, but Orton moves. Orton follows up with the RKO for the win, and Orton will be going to WrestleMania to face Bray Wyatt for the WWE Championship.